Win10 can't open the registry prompt file system error how to do?

Cause analysis:
If the Administrator is enabled on the Win10 system, then when you log in to the system with a Microsoft account, you do not have permission to open the registry.
Workaround:
First, restore the system image file
Because the system file may be changed in the change settings, in order to make the system image file the same as the official file

, in the administrator In the command prompt window, enter the DISM /Online /Cleanup-image /RestoreHealth command, and press Enter to restore the files in the system image file that are different from the official files to the source files of the official system.

After about 10 minutes, the system image file restore operation is successfully completed. As you can see from the picture, there are changes to the system files in the change settings, so it is necessary to restore the system image file once.
Second, change the user account control settings
Method and steps:
1, open the control panel, double-click double: user account;

2, in the open user account window, click: Change user account control settings;

3. In the User Account Control Settings window, we can see that the small slider for adjusting notifications is in the "Always notify" location;

4, then Drag the small slider to the following position: Notify me when the app tries to change my computer (does not reduce the brightness of the desktop) - Don't notify me when I make changes to the Windows settings, then click OK;

5 Enter regedit from the Run dialog box and press Enter to open the Registry Editor.

User Account Control (UAC) is a control mechanism used by Microsoft in its Windows Vista and higher operating systems. The principle is to inform the user whether to use the hard drive and system file authorization for the application to help prevent malicious programs from damaging the system.
So, for user account control settings, it's best to put the small slider in the location (not to lower the desktop brightness) only when the app tries to change my computer. It can prevent malicious programs from damaging the system, as well as allowing certain programs, such as the Registry Editor, to function properly.